OVERVIEW OF LABORATORY DIAGNOSIS OF HUMAN HELICOBACTERIOSIS

Authors

Dhary Alewy Almashhadany Department of Medical Laboratory Science , College of Science , Knowledge University, , Erbil 44001, Iraq
Marwa Dhari Alewi Department of Preventive Dentistry, College of Dentistry, University of Baghdad, Baghdad, Iraq.
Ahlam Taha Mohammed Department of Preventive Dentistry, College of Dentistry, University of Baghdad, Baghdad, Iraq.
Mustafa AbdulMonam Zainel Department of Pharmacy, College of Pharmacy, Knowledge University, Erbil 44001, Iraq.

Helicobacter pylori, laboratory diagnosis, advantages, disadvantages, invasive, noninvasive.

Helicobacter pylori (H.pylori)(HP) is the causative agent of helicobacteriosis. Found often there, it

irritates and inflames the stomach and small intestinal walls. In 2015, an estimated 4.4 billion people

globally carried Helicobacter pylori infections. Adenocarcinoma risk has increased since this bacterium

was originally isolated, suggesting that it may be one of the most prevalent human bacterial infections.

As a result, the World Health Organization (WHO) designated it a Category 1 carcinogen in 1994.

Several assays are available for use in the laboratory for the diagnosis of H. pylori infection from patient

samples. These tests may be broken down into two categories: invasive and non-invasive treatments,

each with its own set of benefits and drawbacks. However, there are limitations to each in terms of

actual clinical use. Clinical context, probability ratio of positive and negative tests, cost-effectiveness

of testing approach, and availability of the test should all factor into the choice of test. Paying close

attention to the positive news about Helicobacter pylori is crucial to reducing the incidence of H. pylori

infection and its associated symptoms. These problems can be avoided altogether if the illness is

caught and treated in time. In this review, we will discuss the methods used to identify

Helicobacteriosis in humans in the laboratory, both invasive and non-invasive.

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